There are a select few who know the pains (both physical and mental) associated with prolonged periods of isolation. Astronauts like Scott Kelly, who spent time on the International Space Station, and D. Marshall Porterfield, NASA’s former Space Life and Physical Sciences Division Director, are all too familiar with the concept of coping with a life spent, periodically, at arm’s length (or longer). Here are some tips on how to live with those overwhelming feelings of loneliness—straight from the experts.

Many of us are currently sequestered indoors, away from our invigorating and purpose-driven routines. It can be argued that those who are confined with others, like roommates, family, or friends, are lucky in that they are at least allowed to engage in conversation with others and aren’t made to struggle with complete loneliness. Wherever you are, you should know that there are benefits to being alone. And, of course, some drawbacks.